Gaucher's Disease
Gaucher's disease is a lysosomal storage disease in which the enzyme β-glucosidase does not function, causing the cerebroside (carbohydrate attached lipid with the amino acid sphingosine) glucocerebroside to build up in the spleen, liver, bone marrow, lungs, kidneys and brain.
Gaucher's Disease is the most common in a rare set of diseases called Lysosomal Storage Diseases. It has a great probability of causing death in early life.
Enlarged spleen due to Gaucher's
Sources for this Page
http://www.gauchercare.com/en/healthcare.aspx
http://themedicalbiochemistrypage.org/gaucherdisease.html
http://www.medstudents.com.br/raredi/raredi2.htm
http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=gaucher
Comments (8)
rryoung@... said
at 2:42 pm on Nov 2, 2009
Put your sources in MLA format.
Candace Boone said
at 3:39 pm on Nov 4, 2009
The picture of the "Gaucher Cell" was interesting because it gave a perspective to from one with the disease and one without.
Hannah Jenkins said
at 7:05 pm on Nov 4, 2009
Interesting disease and pictures. The entire wiki probably could have been "dumbed down" a little bit more; maybe by adding some links to basic definitions, etc.
Mariah Jones said
at 10:52 pm on Nov 4, 2009
I thought that you could have added defintions to help other readers who dont understand what is being said. It also could use more pictures on some pages along with some color
Kathryn Snyder said
at 6:26 am on Nov 5, 2009
I found a lot of the things on here difficult to understand (maybe explain things a little more in-depth?). Overall, this was a very informational site and a very interesting disease.
Cole Brandt said
at 8:49 am on Nov 5, 2009
The "Gaucher Cell" link was very helpful in understanding the structure and foundation of the disease
Kiran Bassi said
at 9:01 am on Nov 5, 2009
Overall, i think that your information helps understand what Gaucher's Syndrome is , but you could've put some pictures on here to make your page look more appealing.
Hannah Jenkins said
at 9:42 am on Nov 5, 2009
I think the information on the discovery of the disease was interesting. It proves how far we have come when they first thought it was a tumor and now they know that is comes all the way down to the lysosome in the cell that causes the disease. Also, I thought it was cool that enzymes are used to cure this disease, because it just is an example of what we learned that the active site and enzyme must match up perfectly for the reaction to speed up.
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