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Diagnosis Bone 11

Page history last edited by Julie Swihart 13 years, 11 months ago


There are a few ways to diagnose Van Buchem's Syndrome



An X-ray is a non-invasive procedure that allows physicians to look at your bones. They may need this procedure to check for fractures and or other bone issues. It works by exposing a small portion of the body to ionization radiation that produces an image of the bone (as seen below). This procedure can be used to diagnose Van Buchem's Syndrome because x-ray images of the bones will show up unusually opaque and bright on the image, as you can see below[1][2].



(Left) This is an X-Ray of a normal hip bone.



(Right) This is an X-Ray of a patient with Van Buchem's Syndrome



Obviously, the image on the left is much darker and

much less opaque than the image on the right.


The image below is a photo of an X-ray machine.






Bone Mineral Density Scan

     A bone mineral density scan is a sort of improved X-ray machine. It uses dual x-ray absorptiometry or DEXA, as well as bone densitometry. This scan is normally used for measuring bone density in older women as a way to catch osteoporosis in its early stages (it is now recommended that women over the age of 65 recieve a scan to help prevent osteoporosis). In diagnosis for Van Buchem's syndrome, it is used in the opposite fashion to check for unusual bone gain instead of loss. Below is a photo of a DEXA scanning machine and also a photo of a normal DEXA scan.

























Van Buchem's Syndrome (Home Page)


Page Authors: Emmie Ryan and Julie Swihart


  1. "Bone X-ray (Radiography) ." RadiologyInfo. 15 Jun 2009. RSNA, Web. 1 Nov 2009. .
  2. K, Veskovic, Hellan M, Nyght C, Balemans W , and Tan J. "Patients with Van Buchem disease, an osteosclerotic genetic disease, have elevated bone formation markers, higher bone density, and greater derived polar moment of inertia than normal.." PubMed.gov. 2003 Dec. PubMed.gov, Web. 1 Nov 2009. .

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