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Causes of Kleinfelter's 3

Page history last edited by Jacob Halbert 14 years, 4 months ago

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Recent studies have shown that the XXY genetic mutation occurs during the process of meiosis (which would be obvious considering we are dealing with non-disjuction). In this process, the 46 chromosomes in a single cell rework themselves to produce 4 daughter cells having 23 chromosomes each. Before the completion of meiosis chromosomes join in homologous pairs and exchange small amounts a genetic material. In women, two X chromosomes pair and in men an X and Y chromosome pair. After they exchange their genetic material, the chromosomes separate, and meiosis continues onto its next phase. Occasionally, the chromosomes move into same cell, producing either an egg with two Xs, or a sperm having both an X and a Y chromosome. When the affected somatic cell joins with its normal counterpart, XXY male is conceived.[1]



 (Chromosomes may move into same cell, producing either an egg with two Xs,

or a sperm having both an X and a Y chromosome.)


  1. XXXY males. Health Grades Inc, 2009. Web. 29 Oct. 2009. .

Comments (4)

Isabel Wenk said

at 11:45 am on Nov 1, 2009

Maybe a picture would help to show visually what happens in each state of meiosis and where something "goes wrong."

William Etienne said

at 12:52 pm on Nov 1, 2009

Thanks :)

Zachary McCormack said

at 6:30 pm on Nov 1, 2009

Or perhaps a video. I noticed a decent amount of pictures but no videos.

Nathan Jeffers said

at 10:25 am on Nov 4, 2009

I like the picture on this page. It really sums up the information above it.

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