What is sickle cell anemia/disease?
Sickle Cell Anemia is a serious disease in which the red blood cells are sickle shaped or C shaped. Sickle Cell is only one type of anemia. Normal red blood cells are disc-shaped and move easily through the blood vessels. Whereas, sickle cells cannot. Sickle cells also contain abmormal hemoglobin. Since the sickle cells contain abnormal hemoglobin, it makes them stiff and sticky and can cause blocks in the blood vessels. These blocks can cause serious pain and also damage major organs in the body.
Symptoms
Macromolecules and Biochemistry
Genetics
History
Are you at risk?
Prevention
Cell Division
Diagnosis
Treatments
Who it Affects
Organizations and Support Groups
Ally Gatmaitan and Alex Schwent
Comments (17)
rryoung@... said
at 2:07 pm on Oct 29, 2009
Yes! This looks great! This is definitely one that I will have others look at as a good example of what should be done. Keep up the good work - I can't wait to see the finished product.
Jacob Halbert said
at 10:15 am on Nov 4, 2009
i like the pictures of the blood vessels because it shows how the red blood cells travel through the blood vessels.
James Berns said
at 10:25 am on Nov 4, 2009
I think that the picture on the diagnosis page is very good in showing you how the sickle- cells can be blocked in the blood vessels.
Tina Le said
at 10:27 am on Nov 4, 2009
I really liked how each page was really descriptive about the different information and how there was a link on the different pages to further explain the topic. For example: you had a link to dictionary.com that had the definition of denature.
Callie Parker said
at 10:28 am on Nov 4, 2009
I like the depth of the information that you had, it really helped me understand sickle cell anemia better.
Dylan Caudill said
at 10:32 am on Nov 4, 2009
All of your pages were really informative and in-depth. I liked all of the pictures you incorporated and how you explained everything clearly. Sickle-Cell Anemia is a very interesting disease and your page helped me learn a lot about it.
Tyler Lasky said
at 10:36 am on Nov 4, 2009
There is a lot of good information regarding the macromolecule, cell division, and genetic background of the disease, which effectively relates to our understanding of Sickle Cell Anemia. The picture/graph under "who it affects" is very helpful as well.
Ashley Gonzalez said
at 11:05 am on Nov 4, 2009
The pictures on all of the pages were good at explaining what was going with each section. The information was in depth and very interesting to learn about.
Sara Adams said
at 10:10 am on Nov 5, 2009
thats unfortunate that they only live into their 40's and 50's with treatment. do you know how long they live without proper health care?
Dylan Caudill said
at 10:12 am on Nov 5, 2009
I found the symptoms page to be very interesting. I never would have thought that sickle-cell disease could cause tumors on your legs or eye problems. Also, the genetic modulation really helped show where and how all of the possible complications occur.
Matthew Riggen said
at 10:20 am on Nov 5, 2009
I thought it interesting that such a small mutation in one protein could cause such a big disease. I also enjoyed the front page picture.
Kaleigh Volpp said
at 10:24 am on Nov 5, 2009
I find it sad that there is really no treatment except daily anitbiotics and frequent blood transfusions. It's interesting that it affects mostly people of African ancestory.
Joshua Miller said
at 10:33 am on Nov 5, 2009
i didnt know that the hemoglobin formd chains that actually caused the sickle shape. i like the multiple pics demonstrating how the sickle cells become clotted more easily than regular cells
Jacob Halbert said
at 10:33 am on Nov 5, 2009
i like the pictures of the blood vessels because it shows how the red blood cells travel through the blood vessels. the top picture shows how normal red blood cells travel through the blood vessels and i like how the bottom picture shows how the deformed sickle cell red blood cells get clogged in the blood vessels.
Zachary McCormack said
at 10:46 am on Nov 5, 2009
Nicely done. One of the better projects I've seen (except for cystic fibrosis). Very well desribed especially on the macromolecules and biochemistry page. The information brought up memories of me looking over those two pages in our bio books the night before the exam. (Denaturing in hemoglobin and such) Thanks for bringing those thoughts back to light.
Emily Ryan said
at 10:58 am on Nov 5, 2009
With all the very severe symptoms like stroke and organ failure it's really sad that there is no way to cure it. Also the treatments seem like they would suck to since you have to get alot of blood transfusions and still have the risk of get those sudden attacks and you would have to go to the doctor alot more often
Andrew Lowhorn said
at 11:10 am on Nov 5, 2009
From the symptoms listed it sounds like it would be hard to find out you have this unless you where tested.
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